John Stamos and Shania Twain Announced to Guest on New Show 'Dr. Odyssey'

Dr. Odyssey is creator Ryan Murphy's first foray back into broadcast television since his work on Glee. And, for the first season of the new ABC drama starring Joshua Jackson, he's pulling out all the stops when it comes to booking guests on a ship that seems to have neverending medical maladies.

The concept of the new series, according to a press release from ABC, involves Jackson's character Max joining a luxury ship "where the staff works hard and plays harder. It’s all hands on deck as Max and his small but mighty medical team navigate unique medical crises and each other, miles from shore." Jackson will be joined in the main cast by Don Johnson, Sean Teale and Philippa Soo.

What perked many people's eyebrows, though, was the official trailer for Dr. Odyssey, released by the series on September 17. In it, we get a glimpse of a slew of guest stars coming to the first season of the show. Here's a list of all the people we knew who will be stepping aboard for Dr. Odyssey Season 1.

Related: Everything to Know About Dr. Odyssey

Dr. Odyssey Season 1 Guest Stars

John Stamos

Have mercy! After appearing on the medical series ER and General Hospital, the Full House star will be triaging once more on Dr. Odyssey.

Shania Twain

The singer will be appearing on the series, though it's unknown if it will be as herself or a character. It remains to be seen if the cruise ship will impress her much.

Gina Gershon

The actress and singer will return to a medical series after starring in NBC's New Amsterdam in 2020 and 2021.

Kelsea Ballerini

The country singer and Grammy nominee will be making one of her first scripted TV appearances on Dr. Odyssey.

Chord Overstreet

The actor and singer got his big break on another Murphy project, starring as Sam on Glee.

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Cheyenne Jackson

The actor and musical theatre star has been a mainstay on one of Murphy's other major projects, the long-running American Horror Story.

Laura Harrier

The up-and-coming model has played a number of notable roles in movies like Spider-Man: Homecoming, BlacKkKlansman, and Murphy's miniseries Hollywood.

Stephanie Suganami

The actress is best known for her recurring role in Power Book II: Ghost on Starz.

Justin Jedlica

The social media personality is most well known as the "Human Ken." He has spent millions of dollars on over 200 cosmetic procedures, ranging from bicep implants to rhinoplasty.

Next, here's everything to know about Ryan Murphy's new series American Sports Story.