“Chicago Med ”Adds“ ”Sarah Ramos and Darren Barnet to Season 10 amid Show Shake-Up

The addition of Ramos and Barnet comes one month after PEOPLE learned Dominic Rains was departing 'Chicago Med'

<p>Michael Buckner/getty; elias tahan</p> From left: Sarah Ramos and Darren Barnet

Michael Buckner/getty; elias tahan

From left: Sarah Ramos and Darren Barnet

Chicago Med is paging Sarah Ramos and Darren Barnet.

NBC announced Ramos and Barnet, both 33, are set to join the hit medical drama as series regulars for its upcoming tenth season.

Ramos will star as Dr. Caitlin Lenox while Barnet will take on the role of Dr. John Frost when the show returns on Wednesday, Sept. 25.

Related: All the Chicago Fire Stars Who've Left the Show — and Why

Lenox is “an ED Attending poised to get Gaffney Medical into shape,” while Frost is “a pediatric resident who is harboring a secret,” a source tells Deadline.

The additions come amid a casting shake-up on the long-time NBC drama series.

PEOPLE learned in June that Dominic Rains — who played Dr. Crockett Marcel — was leaving Chicago Med after five seasons.

<p>George Burns Jr/NBC via Getty</p> Dominic Rains as Dr. Crockett Marcel on "Chicago Med"

George Burns Jr/NBC via Getty

Dominic Rains as Dr. Crockett Marcel on "Chicago Med"

Related: Chicago Fire, Law & Order: SVU and The Voice Among NBC Premieres Announced for Fall 2024

Jessy Schram, Steven Weber and Luke Mitchell are expected to return, joining original castmembers Oliver Platt, S. Epatha Merkerson and Marlyne Barrett.

In addition to the cast change-up, co-showrunners Diane Frolov and Andy Schneider are leaving the series after nine years with Allen MacDonald set to take over.

<p>George Burns Jr/NBC</p> Luigi Sottile as Sean Archer and Jessy Schram as Hannah Asher on 'Chicago Med'

George Burns Jr/NBC

Luigi Sottile as Sean Archer and Jessy Schram as Hannah Asher on 'Chicago Med'

There have been changes elsewhere in the One Chicago franchise over the last year. Eamonn Walker left Chicago Fire as a series regular in the show's season 12 finale, following other departures from the series including Alberto Rosende in December 2023 and Kara Killmer in February.

Meanwhile, Chicago P.D. said farewell to Tracy Spiridakos, who'd played Detective Hailey Upton since 2017, left the series after the season 11 finale in May.

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Chicago Med will return Wednesday, Sept. 25 at 8 p.m. ET on NBC.

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Read the original article on People.