20 Best Infection-Fighting Foods, According to Experts.

Kaitlin Vogel
·10-min read

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While upper respiratory infections generally peak in the winter when we all cram indoors, they can happen any time of year. Keeping your immunity up year-round can prevent colds and the sniffles from forcing you to uninvite yourself to happy hours, cancel vacation plans and drain your PTO.

While many factors affect your immunity—sleep, exercise and stress management, the list goes on—one of the best ways to boost your immunity is by eating foods that fight infection.

Ready to supercharge your immune system? Here are 20 foods recommended by experts—it's time to stock up!.

Related: This Personality Change Could Actually Be a Sign of Infection, According to Doctors

Foods that fight infection

1. Spices, especially clove, oregano, thyme, basil, cinnamon and cumin

Many spices have powerful anti-microbial action, inhibiting the growth and spread of bacteria and fungi, says Dr. Stacie Stephenson, a certified nutrition specialist and CEO of VibrantDoc. This is why they are often used to preserve foods, but including them liberally in your own cooking can help them fight microbes, not just in your food but in you. Basil was one of the herbs called out for its immune-boosting properties in a 2020 review.

2. Chili peppers

Chili peppers contain the compound capsaicin, Dr. Uma Naidoo, MD, a nutritional psychiatrist, professional chef, nutrition specialist and author of the bestselling book This is Your Brain on Food, explains. In addition to many other helpful health benefits, they are rich antioxidants fending off free radicals in the body, but also fending off bacterial infections and may cause mucus to be thinner and be more easily removed from the lungs in certain respiratory infections.

3. Broccoli sprouts

Broccoli sprouts contain bioactives called sulforaphanes that improve immune function, says Dr. William W. Li, MD, an internationally renowned physician, and scientist. Studies have shown broccoli sprouts can even help boost your body’s beneficial response to the flu vaccine. You can put sprouts in a salad or even in a smoothie.

4. Seaweed

Seaweeds and other types of algae, like nori, arame, dulse, kelp and spirulina, contain phenolic compounds, proteins, peptides, fatty acids, polysaccharides and sterols, all of which have demonstrated antimicrobial properties that could help to take out infectious pathogens, Dr. Stephenson explains. Research published in 2021 noted seaweed was a low-fat food with numerous benefits, including antiviral, anticancer and anti-inflammatory properties.

5. Garlic

For centuries, garlic has been used to combat infectious diseases. Although it is not referenced, it is believed that Louis Pasteur described the antibacterial effect of garlic in 1858 for the first time, says Dr. Naidoo. Research has shown that garlic is effective against many gram-positive, gram-negative and acid-fast bacteria. (e.g. salmonella, e. coli, Staph aureus to name a few.

It has been documented that garlic inhibits bad microbes in the gut when compared to good microbes. But garlic is also a prebiotic food source and helps along those gut microbes by feeding them the fiber they need, so one could say it has dual positive effects for infections. Additionally, one 2020 review suggested that spices, including garlic, could help strengthen the immune system and help the body ward off contagious infections.

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6. Mushrooms

Mushrooms contain a natural bioactive substance called beta-D-glucan that activates healthy gut bacteria to enhance immunity, Dr. Li states. The good stuff is in the stem of the mushroom as well as the cap, so eat the stems, too!

7. Citrus fruit

The vitamin C in citrus fruits, like oranges, grapefruits, lemons and limes, is not just a powerful antioxidant but supports both the innate (you were born with it) and adaptive (your body developed it) immune systems in multiple ways, such as promoting wound healing; creating stronger skin, artery and intestinal lining barriers against pathogens; reducing oxidative stress that could worsen infections; killing microbes directly; and cleaning up the by-products of the infection-fighting process, says Dr. Stephenson.

We know people with vitamin C deficiency are more likely to develop infections, and we also know that vitamin C can reduce infection severity. Research from 2023 cited evidence that vitamin C can help uphold the body's immune response, making getting enough essential for fighting diseases, specifically COVID-19.

Other great sources of vitamin C besides citrus fruits include red peppers, strawberries, kiwifruit, papayas, tomatoes, broccoli and kale.

Related: Here's Exactly What Happens to Your Body When You Eat Oranges Every Day

8. Ginger

While ginger is often recommended to help nausea it is high in both antioxidants and anti-inflammatory properties, Dr. Naidoo explains. A research review of 60 studies found that ginger may also be beneficial to other medical conditions including the immune system as ginger contains compounds like beta-carotene and capsaicin. Another study suggested that taking ginger supplements could help with inflammation control in people with autoimmune diseases (keywords: People with autoimmune diseases — the study was not on people without them).

9. Pomegranate

The juice contains ellagitannins that help your gut grow a healthy bacteria called Akkermansiamucinophila, says Dr. Li. This bacterium helps steer your immune system to fight against infections.  A small cup of pomegranate juice can help support Akkermansia in your gut.

10. Pumpkin seeds

Pumpkin seeds are a great source of magnesium, which helps to fight infections by synthesizing antibodies, reducing infection-worsening inflammation and clearing infectious microbes out of the body by binding them to lymphocytes for removal, Dr. Stephenson explains. A 2023-published review hailed pumpkin as a valuable "pharma food," and cited evidence that pumpkin seeds could help the immune system fight infectious diseases.

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11. Apples

In a study where people ate an apple a day, results showed that participants used fewer prescription medications, Dr. Naidoo states. A review noted the numerous health benefits of apples, including antioxidant and anti-inflammatory properties. Apples contain a powerful flavonoid called khellin which may open up airways when you have an infection. They are also high in fiber, which can help reduce inflammation in the body.

12. Blueberries

Blueberries contain anthocyanins, which are natural bioactives that have been shown to increase immune activity in the body while lowering inflammation, Dr. Li explains. Blueberries are available year-round in fresh or frozen form, making them super convenient.

13. Leafy greens

The beta carotene in leafy greens changes into vitamin A during the process of digestion and assimilation, and vitamin A has anti-inflammatory superpowers, says Dr. Stephenson. It also acts as an immune-system enhancer by regulating cellular immune responses, increasing the barrier function of the respiratory and digestive tracts, optimizing the immune function of bone marrow cells, increasing antibody production and inhibiting the development of inflammatory cells.

It’s no wonder vitamin A has been studied as a therapy for infectious diseases, including tuberculosis, malaria and pneumonia. Be sure to eat your greens with a drizzle of olive oil to maximize the bioavailability of the beta carotene.

Related: What Happens If You Don't Eat Vegetables? 

14. Flax and hemp seeds

These contain omega 3 fatty acids, which are anti-inflammatory and proven to decrease the risk for heart disease, breast and colon cancer and neurodegenerative diseases like Alzheimer’s and dementia, Sophia (Dia) Finder, the clinical coordinator of the Applied Nutrition and Dietetics program at Logan University, explains. Omega 3 intake can also reduce the risk for other diseases like depression, ADHD and childhood allergies.

15. Green tea

While more research is needed, evidence suggests EGCG, an anti-inflammatory polyphenol in green tea, can to significantly increase the number of T cells in the spleen and lymph nodes, which act to increase the immune response to infections, Dr. Stephenson states.

16. Calendula petals (marigolds)

Not just a beautiful flower for your garden, calendula petals provide anti-inflammatory benefits and can be sprinkled on salads or soups to add beautiful color to any dish, says Finder.

17. Wild-caught salmon

There is a clear link between sub-optimal vitamin D levels and increased infection rates as well as higher death rates from microbial infections, Dr. Stephenson explains. And wild-caught salmon is one of the few foods that contain a significant dose of vitamin D: 124% or even more of your daily value for a 3.5-ounce portion. (Note that farmed salmon contains significantly less vitamin D than wild-caught salmon.)

Vitamin D supports the production of proteins that are toxic to pathogens. Infection fighters like monocytes, macrophages and thymus tissues all have receptors for vitamin D and are important modulators of the immune response. You can get vitamin D from spending 20 to 30 minutes in the sun on most days, but having salmon 2 or 3 times per week is a good way to further boost your levels, especially if you don’t get regular sun exposure.

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18. Dandelion blossoms

Dandelions contain probiotics associated with good gut health, Finder states. They have a zesty flavor, making them the perfect addition to pesto or soup.

19. Manuka honey

Manuka honey is made from Leptospermum scoparium, also known as the tea tree, found in New Zealand and Australia, says Agatha Repice, the owner of Clean Clear Body. It has antibacterial, and antiviral anti-inflammatory properties.

The enzyme in the honey is called glucose oxidase, which catalyzes the oxidation of glucose to hydrogen peroxide. The honey can be used to treat burns, wounds, ulcers and infections.

20. Nasturtium

Nasturtium is full of antioxidants and has antibacterial and anti-inflammatory properties, Finder explains. Its spicy, peppery flavor makes it a great addition to vegetables like squash or infusing in vinegar.

Next, learn about whether you should drink coffee when you're sick 

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