Militao was suspended for the first leg as Antonio Rudiger impressed against Erling Haaland, but the Chelsea man makes way as Carlo Ancelotti brings the Brazilian in to partner David Alaba.
Recent injury issues for Luka Modric, Ferland Mendy and Dani Ceballos have all abated for Los Blancos, who had minor concerns over Eduardo Camavinga ahead of the game. Camavinga is fit to start and keeps his place at left-back, with Mendy among those named on the bench.
With Real’s domestic title race over, several stars were rested for the weekend win over Getafe including Karim Benzema, Rodrygo and Vinicius Jr.
The trio return to spearhead a 4-3-3 formation, featuring Modric in the midfield alongside Fede Valverde and Toni Kroos.
Eden Hazard, Aurelien Tchouameni and ex-Arsenal midfielder Dani Ceballos are all named on the bench.
Real Madri starting XI: Courtois, Carvajal, Militao, Alaba, Camavinga, Valverde, Kroos, Modric, Rodrygo, Benzema, Vinicius
Subs: Lunin, Vallejo, Nacho, Hazard, Asensio, Odriozola, Lucas, Tchouameni, Ceballos, Rudiger, Mendy, Mariano