Shot by Mario Testino, the campaign also stars Watson's younger brother Alex, 17, Matt Gilmour (son of Pink Floyd's David Gilmour), Max Hurd (the grandson of former British foreign secretary Douglas Hurd) and George Craig.
The foursome showcase pieces from the brand's Burberry Prorsum, Burberry London and Burberry Brit collections.
"The energy of the images and the dynamic cast reflect the different attitudes and expressions of the Burberry guy and girl," says Burberry Chief Creative Officer Christopher Bailey.
See more images on Burberry's Facebook page
Photos: Mario Testino/Burberry