Port Adelaide will try to storm Brisbane's Gabba fortress without key forward Charlie Dixon, who remains sidelined with his foot injury.
But Dixon and fellow injured forward Mitch Georgiades have re-signed with the Power ahead of the AFL finals.
Port could also regain forward Todd Marshall and defender Trent McKenzie for their tough qualifying final test, with Brisbane boasting an imposing 11-0 home record this season.
Dixon is back running after being sidelined for Port's past four games because of a foot fracture and could be a week away from returning.
The 32-year-old has extended his contract at Alberton for another 12 months.
Georgiades has signed a four-year contract extension that commits him until at least the end of 2027, ending speculation about the Western Australia native's future amid reports of interest from rival clubs.
He is recovering from a knee reconstruction that has sidelined the forward since round two.
"It's amazing for the club to give me that much faith and over the next four years to lock in and do as much as I can to play as well as I can," he said.
"It's obviously not the year I've envisioned, but this is a great way to finish the year going into the off-season.
"It was just talking about where's best for me to play my footy and at the end of the day I look at this group, the youth and the players we've got here, it's pretty hard to leave some of my best mates behind as well.
"When it came down to where I'll play my best footy it was here."
Marshall is in the selection mix for Saturday night after missing their round-24 win over Richmond with hip soreness.
McKenzie has not played since round 21 because of a knee injury and will need to pass a fitness test before being cleared to play the Lions.