Chelsea Handler: Angelina Jolie is a "Homewrecker"

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E!’s Chelsea Handler has made it clear: she really doesn’t like Angelina Jolie. Handler, who’s just returned from a Mexican holiday with Jennifer Aniston, focused on The Tourist star during her stand-up comedy routine in Newark, New Jersey, on Friday night.

"She's a homewrecker, she is," Handler said. "She can rescue as many babies from as many countries as she wants to, I don't f--king believe you.

"Because when I look into a woman's eyes and she gives interviews, and she goes, 'Oh, I don't have a lot of female friends'…'cause you're a f--king c--t, that's why. That's why. You're a female and you don't have female friends, you're a f--king bitch."

It's not the first time Handler has targeted Jolie. In August, she called Jolie evil, reading quotes from the Salt star in Us Weekly. "Angelina… it talks about how she’s so fun with her kids – all 18 of them."

"Exhibit A, she recently punked Maddox on the set of ‘Salt,’" Chelsea quoted from the magazine, then read out Angelina’s reported comments: "‘He’s fascinated by the military, so I put on a NATO uniform and said, ‘Someone tell Mad there’s an officer here who wants to say hi.’"

Handler then said: "What a fun mom! You are so fun kitty cat. You go girl!" before adding, "You’re evil and everyone knows it."