Life + Style

Women's vs men's brains

Nov 22 11:14am

The sex of the brain makes men and women more prone to different diseases, according to new research.

Doctors know that women are more likely than men to have depression, anxiety or an eating disorder, while men are at higher risk of Parkinson's disease, the BBC is reporting.

Now scientists say post-mortem and brain imaging studies show that male and female brains are physically different and are even suggesting future disease cures may be "gender-specific".

The sex of a brain is decided in the mother's womb and depends, among other factors, on hormone levels.

Higher levels of testosterone makes a male brain and oestrogen a female one.

Professor Dick Swaab from The Netherlands Institute for Brain Research in Amsterdam, said that because men and women's brains are different "we should be looking at diseases as male and female".

"There is a different sex ratio for neurological and psychiatric diseases," he told the BBC.

"In depression, it is very clear that sex hormones are directly interfering with the stress axis in the brain.

"We have shown that sensitive proteins [receptors] for sex hormones are present in the cells that form the stress axis. In women there are more oestrogen receptors and in men more androgen receptors present.

"That results in higher prevalence of depression in women compared to men because the stress axis is more sensitive.

"The oestrogens are directly affecting the production of the stress peptides.

"So for the same amount of stress in the environment, women are more prone to develop depression than men."

Others have shown that hormone levels could play a part in multiple sclerosis.

Dr Glenda Gillies and colleagues at Imperial College London have been looking at Parkinson's Disease, which is far more common in men than in women.

"The idea is that perhaps oestrogen is being neuroprotective so that the neurones that degenerate in PD don't seem to be as susceptible to the processes in women as they are in men," she said.

5 Comments Report Abuse
1. selina66brisbane - Feb 13 07:15pm
"So for the same amount of stress in the environment, women are more prone to develop depression than men."
Interesting comment........Maybe its because the social networks that support woman, socio environmental, social factors, economic factors are still diproportionatly in favour to male earning capacity then that for woman. Woman face more struggles to get on in life, due to not being able to afford to eg: live on their own, get a mortgage, and are often thrust to the mercy of the still br
2. selina66brisbane - Feb 13 07:16pm
breaucratic less earning capacity and career struggles, that male counterparts do not encounter.
3. myshed2 - Jun 19 10:08pm
Yeah you poor hard done by woman Selina. I feel so guilty being a man. Maybe its because your brain is a lot smaller!!!
4. garryjohnstokes - Mar 15 06:17pm
Silly comment, myshed2.
selina's comment is also invalid .. who has all the shary cary networks : women!
Women's earning capacity is the same as men's IF they do the same job. If they choose to take time off for child raising, they are in the same boat as a man who makes the same choice.
5. inge_thompson2008 - May 25 08:22pm
Its great that we learn to understand each other. In Perth Western Australia the girls are out performing the boys in all subjects for their year 12 exams. They think it is a social problem - so don't worry boys. You are not less intelligent. (Said tongue in cheek)
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